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Methods in Molecular Biology Cancer 18 5: Deutsche Medizinische Wochenschrift Nutrition Reviews 67 6: The American Journal of Clinical Nutrition 91 5: Oligosaccharide and peptidoglycan of Ganoderma lucidum activate the immune response in human mononuclear cells. Phytother Res. Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum. Int Immunopharmacol. Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum Reishi polysaccharides.

Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice. Immunol Invest. Chung WT, et al. Effect of mycelial culture broth of Ganoderma lucidum on the growth characteristics of human cell lines. J Biosci Bioeng. Effect of Ganoderma lucidum on cytokine release by peritoneal macrophages. Iran J Immunol. A Pilot Clinical Trial.

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Toxicol Appl Pharmacol. Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med. The differential immunological activities of Ganoderma lucidum on human pre-cancerous uroepithelial cells. Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: J Sep Sci.

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HPLC method for the determination and pharmacokinetic studies of four triterpenoids in rat plasma after oral administration of Ganoderma lucidum extract. Biomed Chromatogr. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum. Triterpenoids with neurotrophic activity from Ganoderma lucidum.

Nat Prod Res. Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. FEBS Lett.

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  7. Ganoderma lucidum reduces kainic acid-induced hippocampal neuronal damage via inflammatory cytokines and glial fibrillary acid protein expression. Proc West Pharmacol Soc. Ganoderma lucidum extract protects dopaminergic neurons through inhibiting the production of inflammatory mediators by activated microglia. Sheng Li Xue Bao.

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    Epidemiological investigation on mental disorders in 7 areas of China. Hickie I, et al. Br J Psychiatry. Am J Psychiatry.

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    Extract of Ganoderma lucidum prolongs sleep time in rats. Pharmacol Biochem Behav. Sleep-promoting effects of Ganoderma extracts in rats: Potentiation of ganodermic acid S on prostaglandin E 1 -induced cyclic AMP elevation in human platelets. Thromb Res. Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets. Biochem Pharmacol. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum Ling-Zhi in healthy volunteers.

    Anesth Analg. Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. Lipids Health Dis. Effect of oxygenosterols from Ganoderma lucidum and their activity as cholesterol synthesis inhibitors. Appl Environ Microbiol. Ganoderic acid and its derivatives as cholesterol synthesis inhibitors. Isolation and structure determination of a cholesterol esterase inhibitor from Ganoderma lucidum.

    J Microbiol Biotechnol. Metabolic fate of pancreas-derived cholesterol esterase in intestine: J Lipid Res. Lipid-lowering effects of WAY,, an inhibitor of pancreatic cholesteryl ester hydrolase. Comb Chem High Throughput Screen. Hypoglycemic effect and mechanism of a proteoglycan from ganoderma lucidum on streptozotocin-induced type 2 diabetic rats. Eur Rev Med Pharmacol Sci. Antihyperglycemic effect of ganoderma lucidum polysaccharides on streptozotocin-induced diabetic mice.

    Int J Mol Sci. Reishi immuno-modulation protein induces interleukin-2 expression via protein kinase-dependent signaling pathways within human T cells. J Cell Physiol. Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: Nat Med. J Natl Cancer Inst. Role of NK cells in the control of metastatic spread and growth of tumor cells in mice.

    Int J Cancer. The role of natural killer cells in the control of tumor growth and metastasis. Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer. Effects of ganopoly a Ganoderma lucidum polysaccharide extract on the immune functions in advanced-stage cancer patients.

    Extraction of polysaccharide from Ganoderma lucidum and its immune enhancement activity. Int J Biol Macromol. Inhibition by fibrin coagulation of lung cancer cell destruction by human interleukinactivated killer cells. Jpn J Cancer Res. Ganoderma lucidum polysaccharides eradicates the blocking effect of fibrinogen on NK cytotoxicity against melanoma cells.